My publications


2019


  • Structural white matter networks in myotonic dystrophy type 1. A diffusion tensor imaging study

    • Authors: van Dorst M, Okkersen K, Kessels RPC, Meijer FJA, Monckton DG, van Engelen BGM*, Raaphorst J*, Tuladhar AM*, for the OPTIMISTIC consortium

    • Journal: NeuroImage: Clinical

    • 2019;21:101615

  • Apathy is associated with large-scale white matter network disruption in small vessel disease

    • Authors: Tay J, Tuladhar AM, Hollocks MJ, Brookes RL, Tozer DJ, Barrick TR, Husain M, de Leeuw FE, Markus HS

    • Journal: Neurology

    • 2019 Mar 12;92(11):e1157-e1167

2018


  • Pregnancy and Ischemic stroke: a practical guide to management

    • Authors: Alebeek ME, de Heus R, Tuladhar AM, de Leeuw FE

    • Journal: Current Opinion in Neurology

    • 2018;31(1):44-51

  • Free water is a key determinant of diffusion imaging alterations and clinical status in cerebral small vessel disease

    • Authors: Duering M, Baykara E, Tuladhar AM, Gesierich B, Konieczny M, Malik R, Franzmeier N, Ewers M, Jouvent E, Schmidt R, Biessels GJ, de Leeuw FE, Pasternak O, Dichgans M

    • Journal: Alzheimers and Dementia

    • 2018;14)6):764-774

  • Serum Neurofilament Light Chain is Related to MRI and Clinical Measures in Small Vessel Disease

    • Authors: Duering M, Konieczny M, Tiedt S, Baykara E, Tuladhar AM, Lyrer P, Engelter ST, Gesierich B, Achmüller M, Barro C, Adam R, Ewers M, Dichgans M, Kuhle J, de Leeuw FE, Peters N

    • Journal: Journal of Stroke

    • 2018;20(2):228-238

  • Cerebral small vessel disease: from focal to global perspective

    • Authors: ter Telgte A, van Leijsen EMC, Wiegertjes K, Klijn CJM, Tuladhar AM, de Leeuw FE

    • Journal: Nature Reviews Neurology

    • 2018. 14(7):387-398

  • Progression of white matter hyperintensities preceded by heterogeneous decline of microstructural integrity

    • Authors: van Leijsen EMC, Bergkamp MI, van Uden IWM, Ghafoorian M, van der Holst HM, Norris DG, Platel B, Tuladhar AM, de Leeuw FE

    • Journal: Stroke

    • 2018;49(6):1386-1393

  • Investigating the origin and evolution of cerebral small vessel disease: the RUN DMC – InTENse study

    • Authors: ter Telgte A, Wiegertjes K, Tuladhar AM, Noz MP, Marques JP, Gesierich B, Huebner M, Mutsaerts H-J MM, Elias-Smale SE, Beelen M-J, Ropele S, Kessels RPC, Riksen NP, Klijn CJM, Norris DG, Duering M and de Leeuw FE

    • Journal: European Stroke Journal

    • 2018; May

  • Epidemiology, aetiology, and management of ischaemic stroke in young adults

    • Authors: Ekker MS, Boot EM, Singhal AB, Tan KS, Debette S, Tuladhar AM, de Leeuw FE

    • Journal: Lancet Neurology

    • 2018; 17(9):790-801

  • Hoofdpijn als uiting van sinus cavernosus tromboflebitis [Headache: consider cavernous sinus thrombophlebitis]

    • Authors: Deliran S, Sondag L, Leyten Q, Tuladhar AM, Meijer A

    • Journal: Nederlands Tijdschrift voor Geneeskunde

    • 2018; August 16;162

  • Brain atrophy and strategic lesion location increases risk of parkinsonism in cerebral small vessel disease

    • Authors: Bergkamp M, Tuladhar AM, van der Holst HM, van Leijsen EMC, Ghafoorian M, van Uden IWM, van Dijk E, Norris DG, Platel B, Esselink RAJ, de Leeuw FE

    • Journal: Parkinsonism Related Disorders

    • 2018; November 8

  • The risk of nursing home admission in small vessel disease

    • Authors: Bergkamp M, Wissink JG, van Leijsen EM, Ghafoorian M, Norris DG, van Dijk E, Platel B, Tuladhar AM, de Leeuw FE

    • Journal: Stroke

    • 2018; November; 49(11):2659-2665

  • Memory decline in elderly with cerebral small vessel disease explained by temporal interactions between white matter hyperintensities and hippocampal atrophy

    • Authors: van Leijsen EMC, Tay J, van Uden IWM, Kooijmans ECM, Bergkamp MI, van der Holst HM, Ghafoorian M, Platel B, Norris DG, Kessels RPC, Markus HS, Tuladhar AM, de Leeuw FE

    • Journal: Hippocampus

    • 2018. Oct 11

  • Cognitive consequences of regression of cerebral small vessel disease

    • Authors: van Leijsen EMC, Bergkamp MI, van Uden IWM, Cooijmans S, Ghafoorian M, van der Holst HM, Norris DG, Kessels RPC, Platel B, Tuladhar AM, de Leeuw FE

    • Journal: European Stroke Journal

    • 2018. Dec

  • Herseninfarcten op jonge leeftijd

    • Authors: Boot EM, Ekker MS, de Leeuw FE, Tuladhar AM

    • Journal: Nervus

    • 2018; sept: Jaargang 3

  • Herseninfarcten op jonge leeftijd

    • Authors: Boot EM, Ekker MS, de Leeuw FE, Tuladhar AM

    • Journal: Nervus

    • 2018; sept: Jaargang 3

2017


  • Brain imaging in myotonic dystrophy type 1: A systemic review

    • Authors: Okkersen K, Monckton DG, Le N, Tuladhar AM, Raaphorst J, van Engelen BGM

    • Journal: Neurology

    • 2017; 89(9):960-969

  • Nonlinear temporal dynamics of cerebral small vessel disease: The RUN DMC study

    • Authors: van Uden IWM, van Leijsen EM, Ghafoorian M, Bergkamp MI, Lohner V, Kooijmans ECM, van der Holst HM, Tuladhar AM, Norris DG, van Dijk EJ, Rutten-Jacobs LCA, Platel B, Klijn CJM, de Leeuw FE

    • Journal: Neurology

    • 2017; 89(15):1569-1577

  • Rich club organization in cerebral small vessel disease

    • Authors: Tuladhar AM, Lawrence A, Norris DG, Markus H, de Leeuw FE

    • Journal: Human Brain Mapping

    • 2017; Apr 38(4):1751-1766

  • Disease progression and regression in sporadic SVD

    • Authors: van Leijsen EM, de Leeuw FE, Tuladhar AM

    • Journal: Clinical Science

    • 2017. Jun 1; 131(12):1191-1206

  • Increased risk for cerebrovascular event in young cancer survivors: the down side of surviving cancer

    • Authors: Tuladhar AM, de Leeuw FE

    • Journal: Circulation

    • 2017; 135(35):1211-1213

  • White matter changes and gait decline in cerebral small vessel disease

    • Authors: Tuladhar AM, van der Holst HM, Zerbi V, van Uden IWM, de Laat KF, van Leijsen EM, Ghafoorian M, Platel B, Bergkamp M, van Norden AGW, Norris DG, van Dijk E, de Leeuw FE

    • Journal: NeuroImage: Clinical

    • 2018; 17:731-738

2016


  • White matter microstructural damage on diffusion tensor imaging in cerebral small vessel disease: the clinical consequences

    • Authors: Pasi M, van Uden IW, Tuladhar AM, de Leeuw FE, Pantoni L

    • Journal: Stroke

    • 2016;47(6):1679-84

  • Structural network efficiency predicts conversion to dementia

    • Authors: Tuladhar AM, van Uden IWM, Rutten-Jacobs L, Lawrence A, van der Holst HM, van Norden AGW, de Laat KF, van Dijk E, Claassen JAHR, Kessels RPC, Markus HS, Norris DG, de Leeuw FE

    • Journal: Neurology

    • 2016; Feb 17. Mar;86(12):1112-9

  • Factors associated with 8-year mortality in older patients with cerebral small vessel disease: The Radboud University Nijmegen Diffusion Tensor and Magnetic Resonance Cohort (RUN DMC) study

    • Authors: van der Holst HM, van Uden IWM, Tuladhar AM, de Laat KF, Norden AGW, van Norris DG, van Dijk E, de Leeuw FE

    • Journal: JAMA Neurology

    • 2016. Feb 1. doi: 10.1001/jamaneurol.2015.4560

  • Diffusion tensor imaging of the hippocampus predicts the risk of dementia; the RUN DMC study

    • Authors: Tuladhar AM, van Uden IWM, van der Holst HM, van Leijsen EM, van Norden AGW, de Laat KF, Rutten-Jacobs LCA, van Norris DG, Claassen JAHR, van Dijk E, Kessels RPC, de Leeuw FE

    • Journal: Stroke

    • 2016; Jan;37(1):327-37

  • Structural network connectivity and cognition in cerebral small vessel disease

    • Authors: Tuladhar AM, van Dijk E, van Norden AGW, Zwiers MP, de Laat KF, Shumskaya E, Norris DG, de Leeuw FE

    • Journal: Human Brain Mapping

    • 2016; 37(1):300-10

  • White matter microstructural damage on diffusion tensor imaging in cerebral small vessel disease: the clinical consequences

    • Authors: Pasi M, van Uden IWM, Tuladhar AM, de Leeuw FE, Pantoni L

    • Journal: Stroke

    • 2016; 47(6):1679-84

  • Late onset depressive symptoms increase the risk of dementia in small vessel disease

    • Authors: van Uden IWM, van der Holst HM, van Leijsen EM, Tuladhar AM, van Norden AGW, de Laat KF, Claassen JAHR, van Dijk E, Kessels RPC, Richard E, Tendolkar I, de Leeuw FE

    • Journal: Neurology

    • 2016; 87(11):1102-9

  • A novel imaging marker for small vessel disease and related cognitive impairment based on skeletonization of white matter tracts and diffusion histograms

    • Authors: Baykara E, Gesierich B, Tuladhar AM, Ropele S, Jouvent E, Chabriat H, Ertl-Wagner B, Ewers M, Schmidt R, de Leeuw FE, Biessels GJ, Dichgans M, Duering M

    • Journal: Annals of Neurology

    • 2016; 80(4):581-92

  • Remote white matter integrity increases the risk of long-term cognitive impairment after stroke in young adults

    • Authors: Schaapsmeerders P, Tuladhar AM, Arntz RM, Franssen S, Maaijwee NAM, Rutten-Jacobs LCA, Schoonderwaldt H, Dorresteijn LDA, van Dijk EJ, Kessels RPC, de Leeuw FE

    • Journal: Stroke

    • 2016; 47(10):2517-25

  • Baseline cerebral small vessel disease and white matter structural integrity are not associated with gait decline after 5 years

    • Authors: van der Holst HM, van Uden IWM, de Laat KF, van Leijsen EM, van Norden AGW, Norris DG, van Dijk E, Tuladhar AM, de Leeuw FE

    • Journal: Movement Disorders Clinical Practice

    • 2016; 4(3):374-382

  • Baseline cerebral small vessel disease and white matter structural integrity are not associated with gait decline after 5 years

    • Authors: van der Holst HM, van Uden IWM, de Laat KF, van Leijsen EM, van Norden AGW, Norris DG, van Dijk E, Tuladhar AM, de Leeuw FE

    • Journal: Movement Disorders Clinical Practice

    • 2016; 4(3):374-382

2015


  • Lower Ipsilateral Hippocampal Integrity after Ischemic Stroke in Young Adults: A Long-term Follow-up Study

    • Schaapsmeerders P, Tuladhar AM, Maaijwee NAM, Rutten-Jacobs LCA, Arntz RM, Schoonderwaldt H, Dorresteijn LDA, van Dijk EJ, Kessels RPC, de Leeuw FE

    • Journal: PLos One

    • 2015. Oct 13;10(10):e0139772. doi: 10.1371/journal.pone.0139772

  • Baseline white matter microstructural integrity is not related to cognitive decline after 5 years; the RUN DMC study

    • Authors: van Uden IWM, van der Holst HM, Schaapsmeerders P, Tuladhar AM, van Norden AGW, de Laat KF, Norris DG, Claassen JAHR, van Dijk E, Richard E, Kessels RP, de Leeuw FE

    • Journal: BBA Clinical

    • 2015. Oct 26;4:108-114

  • White matter and hippocampal volume predict the risk of dementia in patients with cerebral small vessel disease: The RUN DMC study

    • Authors: van Uden IWM, van der Holst HM, Tuladhar AM, Norden AGW, de Laat KF, Rutten-Jacobs LCA, van Norris DG, Claassen JAHR, van Dijk E, Kessels RPC, de Leeuw FE

    • Journal: Journal of Alzheimer’s Disease

    • 2015;49(3):863-73

  • Cerebral small vessel disease and incident parkinsonism: The RUN DMC study

    • Authors: van der Holst HM, van Uden IWM, Tuladhar AM, de Laat KF, Norden AGW, van Norris DG, van Dijk E, Esselink R, de Leeuw FE

    • Journal: Neurology

    • 2015;3:15-36

  • Cognitive functioning, depression, fatigue and quality of life among long-term survivors of head and neck cancer

    • Authors: Wilbers J, Kappelle AC, Versteeg L, Tuladhar AM, Boogerd B, Dorresteijn LD, Kaanders JH, Kessels RPC, van Dijk EJ

    • Journal: Neuro-Oncology Practice

    • 2015

  • Cohort study ON Neuroimaging, Etiology and Cognitive consequences of Transient neurological attacks (CONNECT): study rationale and protocol

    • Authors: Van Rooij F, Tuladhar AM, Kessels RPC, Vermeer SE, Goraj, BM, Koudstaal PJ, Norris DG, de Leeuw FE, van Dijk E

    • Journal: BMC Neurolog

    • 2015;15:36

  • Diffusion Tensor Imaging in the diagnostic work-up of parkinsonism

    • Authors: Meijer FJA, van Rumund A, Tuladhar AM, Aerts MB, Titulaer I, Esselink RAJ, Bloem BR, Verbeek MM, Goraj B

    • Journal: Neuroradiology

    • 2015;57(7):655-69

  • Ipsilateral hippocampal atrophy is associated with long-term memory dysfunction after ischemic stroke in young adults

    • Authors: Schaapsmeerders P, van Uden IWM, Tuladhar AM, Maaijwee NA, van Dijk EJ, Rutten-Jacobs LC, Arntz RM, Schoonderwaldt HC, Dorresteijn LD, de Leeuw FE, Kessels RP

    • Journal: Human Brain Mapping

    • 2015;36(7):2432-42

  • White matter integrity in small vessel disease is related to cognition

    • Authors: Tuladhar AM, Norden AGW, de Laat KF, van Norris DG, Zwiers MP, van Dijk E, de Leeuw FE

    • Journal: NeuroImage Clinical

    • 2015;7:518-24

  • The relation between white matter hyperintensities, cortical thickness and cognition

    • Authors: Tuladhar AM, Reid A, Shumskaya E, de Laat KF, van Norden AGW, van Dijk E, Norris DG, de Leeuw FE

    • Journal: Stroke

    • 2015;46(2):425-32

2014


  • White matter integrity and depressive symptoms in cerebral small vessel disease, the RUN DMC study

    • Authors: Tuladhar AM, van Uden IW, de Laat KF, van Norden AGW, van Dijk E, Norris DG, Tendolkar I, de Leeuw FE

    • Journal: American Journal of Geriatric Psychiatry

    • 2014;23(5):525-35

  • Long term cerebral and vascular complications after irradiation of the neck in head and neck cancer patients: a prospective cohort study: study rationale and protocol

    • Authors: Wilbers J, Kappelle AC, Kessels RP, Steens SC, Meijer FJA, Kaanders JH, Haast RA, Versteeg LE, Tuladhar AM, de Korte CL, Hansen HH, Hoebers FJ, Boogerd W, van Werkhoven ED, Nowee ME, Hart G, Bartelink H, Dorresteijn LD, van Dijk EJ

    • Journal: BMC Neurology

    • 2014;14:132

2013


  • Neurological complication after chewing Khat leaves

    • Authors: Tuladhar AM, Boogaarts H., de Leeuw HE, van Dijk E

    • Journal: Cerebrovascular diseases

    • 2013;36(2):158-9

  • Spinale durale arterioveneuze fistel – Vaak pas laat herkend

    • Authors: Wilbers J, Meijer FJA, Tuladhar AM, de Vries J, van Dijk E, Boogaarts JD

    • Journal: Nederlands Tijdschrift voor Geneeskunde

    • 2013;157(12):A5909

  • Neurologische complicaties van Listeria-infectie

    • Authors: Tuladhar AM, Boerman RH, van Hall H, van de Beek D, Quinten LH

    • Journal: Neurologische complicaties van Listeria-infectie

    • not specified

  • Physical inactivity is related to loss of white matter integrity

    • Authors: Tuladhar AM, Gons R. van Uden IVM, de Laat KF, van Norden AGW, Zwiers MP, Norris DG, van Dijk E, de Leeuw FE

    • Journal: Neurology

    • 2013;81(11):971-6

  • Altered default mode network in stroke patients with impaired episodic memory

    • Authors: Tuladhar AM, Snaphaan L, Shumskaya E, Rijpkema M, Fernandez G, Norris DG, de Leeuw FE

    • Journal: PLos One

    • 2013;8(6)e66556

  • Dystonic head tremor and cerebellar white matter changes in a patient with POLG mutation

    • Authors: Tuladhar AM, Meijer A, van de Warrenburg B

    • Journal: Journal of Neurology

    • 2013;260(3):903-5

  • Microstructural integrity of the cingulum is related to verbal memory performance in elderly with cerebral small vessel disease: the RUN DMC study

    • Authors: Tuladhar AM, van der Holst HM, van Norden AGW, de Laat KF, van Uden IWM, van Oudheusden LJB, Zwiers MP, Norris DG, Kessels RPC, de Leeuw FE

    • Journal: NeuroImage

    • 2013;65:416-23

2011


  • Loss of white matter integrity is associated with gait disorders in cerebral small vessel disease

    • Authors: Tuladhar AM, de Laat K, van Norden AG, Norris DG, Zwiers MP, de Leeuw FE

    • Journal: Brain

    • 2011;134(1):73-83

2010


  • Poststroke dementia – what’s in the name?

    • Authors: Tuladhar AM & de Leeuw FE

    • Journal: Nature Reviews Neurology

    • 2010;6(2):63-4

2007


  • Patieto-occipital sources account for the increase in alpha activity with working memory load

    • Authors: Tuladhar AM, ter Huurne N, Schoffelen JM, Maris E, Oostenveld R, Jensen O

    • Journal: Human Brain Mapping

    • 2007;28(8):785-92